Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure

Bhaskar Chanda Stem Cell White and colleagues define the critical early steps of melanoma development from adult melanocyte stem cells. Although stem cell quiescence can work as a tumor suppressor in cutaneous melanoma formation, UV radiation can initiate melanoma formation from these quiescent melanocyte stem cells via an immune-dependent process.

from Cell Stem Cell
via Bhaskar Chanda UHN


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