Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia

Bhaskar Chanda Stem Cell Goldman and colleagues use mice chimerized with human patient-derived glial progenitor cells to find out whether glia contribute to childhood-onset schizophrenia. The defects in cell differentiation, myelination, and behavior they see strongly suggest that glial cells do, in fact, have a previously unappreciated role in the pathogenesis of this disease.

from Cell Stem Cell
via Bhaskar Chanda UHN


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