Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State

Bhaskar Chanda Stem Cell In this article, Deng and colleagues show that functional neurons and hepatocytes can be induced from fibroblasts via a chemically induced and highly expandable XEN-like state, bypassing the pluripotent stage. This featured lineage reprogramming strategy would be generalized for generating other functional desirable cell types.

from Cell Stem Cell
via Bhaskar Chanda UHN


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