Induction of Expansion and Folding in Human Cerebral Organoids

Bhaskar Chanda Stem Cell The growth and structural formation of the human cortex can be modeled in vitro using cerebral organoids. In this article, Li, Muffat, and colleagues show that enhancing the PTEN-AKT signaling pathway leads to the generation of human cerebral organoids that are expanded in size and display surface folding.

from Cell Stem Cell
via Bhaskar Chanda UHN


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