A Quiescent High Stem Cell Population Is Required for Maintenance of the Mammary Gland

Bhaskar Chanda Stem Cell Bcl11b interacts with cell-cycle regulators to induce a quiescent state. Cai et al. describe a quiescent mammary stem cell population labeled by Bcl11b and located at the luminal-basal interface that supports mammary gland regeneration. Bcl11b sustains this population by inducing cell-cycle regulators that promote the dormant state.

from Cell Stem Cell http://ift.tt/2ht7KHr
via Bhaskar Chanda UHN


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