Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle

Bhaskar Chanda Stem Cell Li and colleagues reported that tissue damage enables in vivo reprogramming in skeletal muscle, which can arise from muscle stem cells. They also show that damage-induced cellular senescence promotes cellular plasticity through release of secreted proteins, including IL-6. Their findings could have implications for developing therapeutic lineage reprogramming strategies.

from Cell Stem Cell
via Bhaskar Chanda UHN


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