A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells

Bhaskar Chanda Stem Cell Mazzoni and colleagues show that transcription factor-directed programming of ESCs to motor neurons involves two distinct regulatory modules that converge when programming TFs are relocated by the activity of factors induced in the earlier stage of the process.

from Cell Stem Cell http://ift.tt/2hkeXy3
via Bhaskar Chanda UHN


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