Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy

Bhaskar Chanda Stem Cell Stem cells interact with the surrounding extracellular environment to facilitate tissue plasticity. Fry and colleagues report that skeletal muscle myogenic progenitor cells (MPCs) secrete exosomes containing miR-206, which regulates fibrogenic cell collagen expression through repression of Rrbp1. MPC-mediated regulation of the muscle extracellular environment is necessary during early myofiber growth.

from Cell Stem Cell
via Bhaskar Chanda UHN


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