Conversion of Terminally Committed Hepatocytes to Culturable Bipotent Progenitor Cells with Regenerative Capacity
Bhaskar Chanda Stem Cell Katsuda et al. report reprogramming of mature hepatocytes into expandable bipotent progenitors, CLiPs, using small molecules. CLiPs substantially repopulate injured mouse livers, suggesting the potential clinical application of this approach.
from Cell Stem Cell http://www.cell.com/cell-stem-cell/fulltext/S1934-5909(16)30347-2?rss=yes
via Bhaskar Chanda UHN