A Transient Developmental Hematopoietic Stem Cell Gives Rise to Innate-like B and T Cells

Bhaskar Chanda Stem Cell Beaudin and colleagues demonstrate the existence of a developmentally restricted hematopoietic stem cell with robust capability to generate innate-like lymphocytes. These data show that a population of rapidly proliferating fetal HSCs that extinguish prior to the establishment of adult hematopoiesis serve as the elusive cells of origin for layered immune development.

from Cell Stem Cell http://ift.tt/2cOgewQ
via Bhaskar Chanda UHN


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