Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ

Bhaskar Chanda Stem Cell Reprogramming and lineage conversions have highlighted the plasticity of differentiated cell states. Here Panciera et al. build on these principles by showing that expression of YAP/TAZ can convert a range of differentiated cells into somatic stem cells of the same tissue, respecting lineage restrictions.

from Cell Stem Cell
via Bhaskar Chanda UHN


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