Dnmt3a and Dnmt3b Associate with Enhancers to Regulate Human Epidermal Stem Cell Homeostasis

Bhaskar Chanda Stem Cell Rinaldi et al. show that Dnmt3a and Dnmt3b associate to and activate enhancers. Whereas Dnmt3a induces enhancer DNA hydroxymethylation, Dnmt3b promotes enhancer DNA methylation. Both proteins regulate epidermal SC homeostasis.

from Cell Stem Cell http://ift.tt/2azaANu
via Bhaskar Chanda UHN


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