Molecular Obstacles to Clinical Translation of iPSCs

Bhaskar Chanda Stem Cell Several studies have suggested that some iPSC clones display tumorigenic and immunogenic potential as well as variations in their differentiation potential, thus raising concerns about their utility and safety in the clinical setting. Tapia and Schöler discuss these molecular obstacles and how they may affect clinical translation of iPSC technology.

from Cell Stem Cell
via Bhaskar Chanda UHN


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