Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche

Bhaskar Chanda Stem Cell Ye et al. show that LSCs co-opt the adipose tissue niche to create a microenvironment that supports leukemic growth and resistance to chemotherapy. They also detect metabolically and functionally distinct mouse and human LSC subpopulations delineated by expression of the fatty acid transporter CD36.

from Cell Stem Cell http://ift.tt/29dR2vF
via Bhaskar Chanda UHN


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