CD82/KAI1 Maintains the Dormancy of Long-Term Hematopoietic Stem Cells through Interaction with DARC-Expressing Macrophages

Bhaskar Chanda Stem Cell Hur et al. show that a conserved interaction between CD82/KAI1 on the surface of LT-HSCs and DARC on niche macrophages maintains LT-HSC quiescence through signaling-based inhibition of cell-cycle progression.

from Cell Stem Cell http://ift.tt/1RQWvDT
via Bhaskar Chanda UHN

Advertisements

Tags: , , , , , , ,

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: