Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis

Bhaskar Chanda Stem Cell Sharma, Ott, and colleagues show that expression of a key set of four transcription factors can reprogram hepatic myofibroblasts to induced hepatocyte-like cells in vivo and reduce liver fibrosis, suggesting that direct in vivo reprogramming may be an effective treatment approach for chronic liver disease.

from Cell Stem Cell http://ift.tt/1UmSgor
via Bhaskar Chanda UHN

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