Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells

Bhaskar Chanda Stem Cell Zhang and colleagues show that, as they found previously in mouse, injection of a histone demethylase improves the efficiency of human SCNT reprogramming. Using this approach they were able to reduce variability in success from different egg donors and derive human NT-ESC lines from patients with age-related macular degeneration.

from Cell Stem Cell http://ift.tt/20d9WFx
via Bhaskar Chanda UHN

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