AMPK Protects Leukemia-Initiating Cells in Myeloid Leukemias from Metabolic Stress in the Bone Marrow

Bhaskar Chanda Stem Cell Saito et al. show that deletion of AMPK from AML cells disrupts their glucose metabolism and redox homeostasis and that deletion of AMPK synergizes with metabolic stress caused by dietary restriction to suppress AML.

from Cell Stem Cell http://ift.tt/1N4TeDG
via Bhaskar Chanda UHN

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