Rho-Signaling-Directed YAP/TAZ Activity Underlies the Long-Term Survival and Expansion of Human Embryonic Stem Cells

Bhaskar Chanda Stem Cell Ohgushi et al. show that a regulatory pathway involving Rho, YAP/TAZ, and the actin cytoskeleton that is specific for the pluripotent state enables human embryonic stem cells to undergo long-term survival and expansion in culture.

from Cell Stem Cell http://ift.tt/1hhE8Ni
via Bhaskar Chanda UHN


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