Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury

Bhaskar Chanda Stem Cell Llorens-Bobadilla et al. perform single-cell RNA sequencing of acutely isolated neural stem cells (NSCs) from the adult SVZ, identifying lineage-primed NSCs residing along a continuum of co-existing states between dormancy and activation. NSCs in different states possess unique molecular features and exhibit differential responses to acute ischemic brain injury.

from Cell Stem Cell
via Bhaskar Chanda UHN


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