Single-Cell Transcriptomics Reveals a Population of Dormant Neural Stem Cells that Become Activated upon Brain Injury

Bhaskar Chanda Stem Cell Llorens-Bobadilla et al. perform single-cell RNA sequencing of acutely isolated neural stem cells (NSCs) from the adult SVZ, identifying lineage-primed NSCs residing along a continuum of co-existing states between dormancy and activation. NSCs in different states possess unique molecular features and exhibit differential responses to acute ischemic brain injury.

from Cell Stem Cell http://ift.tt/1Ib3MKy
via Bhaskar Chanda UHN

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