Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells

Bhaskar Chanda Stem Cell Saitou and colleagues report induction of human primordial germ cell-like cells (hPGCLCs) from pluripotent stem cells. hPGCLC and mouse PGC specification rely on similar signaling pathways but utilize distinct transcriptional programs, highlighting differences in PGC induction and demonstrating the utility of hPGCLCs for studying human germ cell development in vitro.

from Cell Stem Cell http://ift.tt/1gDLyuk
via Bhaskar Chanda UHN

Advertisements

Tags: , , , , , , ,

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: