Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

Bhaskar Chanda Stem Cell Wilson et al. combine single-cell functional assays with flow cytometric index sorting and single-cell gene expression assays to reveal gene expression programs of HSCs with durable self-renewal potential in transplantation assays. They also demonstrate the broader applicability of this approach for linking key molecules with defined stem cell functions.

from Cell Stem Cell
via Bhaskar Chanda UHN


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