Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability

Bhaskar Chanda Stem Cell Zhao et al. identify Filia as an ESC-specific regulator of genomic stability that is induced by genotoxic stress. Functional characterization highlights dynamic subcellular translocation and roles in governing multiple DNA damage response pathways, including stimulation of PARP1 enzymatic activity.

from Cell Stem Cell
via Bhaskar Chanda UHN


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