ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency

Bhaskar Chanda Stem Cell Kida et al. show that upregulation of ERRα or ERRγ is required for a metabolic switch involving OXPHOS that is essential for iPSC generation and that early upregulation of ERRs marks cells that are destined to go on to be reprogrammed.

from Cell Stem Cell http://ift.tt/1aa4e0M
via Bhaskar Chanda UHN

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