Long Non-Coding RNAs Control Hematopoietic Stem Cell Function

Bhaskar Chanda Stem Cell Luo et al. perform deep RNA sequencing of hematopoietic stem cells (HSCs), identifying previously unannotated long non-coding RNAs (lncRNAs) enriched in this cell population. Functional characterization of several HSC-enriched lncRNAs demonstrated roles in regulating HSC differentiation and self-renewal and revealed genomic binding to hematopoietic transcription factor binding sites.

from Cell Stem Cell http://ift.tt/1Gwm1dh
via Bhaskar Chanda UHN


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