SCNT-Derived ESCs with Mismatched Mitochondria Trigger an Immune Response in Allogeneic Hosts

Bhaskar Chanda Stem Cell Deuse et al. report that SCNT-derived mouse ESCs trigger an immune rejection in spite of their matching with the entire nuclear genome of the recipient mouse strain. Their findings reveal that mismatched mitochondria can be sufficient to elicit an allogeneic response.

from Cell Stem Cell http://ift.tt/1Hqwzg5
via Bhaskar Chanda UHN

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